{In advance of ??? soon after applying ????????????? ???????? ????????? ?????? ??? ???????? ??????? ????????? ????????? |???????? ??????????? ??????? ?????????? ???? ????????? ??????????????-???? ???????????? ?????? ??? adults ???? 50 % ??? ??????? ????????????? ?????????? ??????? ??????????? ???????? ???????????????????? ????????????? ????? ?????